I would be fairly certain the mean time between failures was factored into Honda's decision on what fluid to use. There is certainly and without a doubt a calculation involved for how many hours the engine and transmission (and any other part on the vehicle) is designed to withstand without failure. Hopefully, you get a factory freak and run 500,000 miles with no issues. Realistically, Honda probably designed all major mechanical parts on these vehicles with a goal in mind for MTBF. The fluids with lubrication are a big part of this equation. I would run Amsoil without any hesitation because synthetic fluids are inherently more protective against sheering and deposit build-up. Auto manufacturers are in the business to make money. A broken car means it's time to buy a new one and more revenue for them. Thankfully, Honda apparently aims for the high end on MTBF and is very successful in making sure we get what we paid for. However, if I can use another fluid and get a little more time before it's time to trade or scrap it, why not go for it?